The First Vial

The solemn moment will come when the command will be given, and the vials be poured out. To the seven angels it will he said,
Go your ways, and pour out the vials of the wrath of God upon the earth (Rev. 16:1).
This series of judgments evidently begins after the beast has been fully manifested, and his image set up; for the first vial is poured out on those who are connected with the abomination of desolation.
The first went and poured out his vial upon the earth; and there fell a noisome and grievous sore upon the men which had the mark of the beast, and upon them which worshipped his image (Rev. 16:2).