(properly
DISEASE
i. Current preconceptions prevalent in time of Christ.
ii. References to sickness and disease in the Gospels.
1. Diseases resulting in physical defect or incapacity.
2. Fever and allied diseases.
3. Cutaneous affections.
4. Dropsy.
5. Nervous diseases.
6. Nervous and psychical disorders.
Literature.
i. Current preconceptions in time of Christ.—Two ideas respecting disease had a powerful influence on conceptions current in our Lord’s day: (1) The belief that all sickness and physical disease and pain were penalties imposed as the result of sin; (2) the idea that demonic agency was concerned with all human suffering. These kindred and allied ideas have been common among ancient peoples, and were strongly developed among the Babylonians, Persians, and Greeks.
Sayce, in his Hibbert Lectures (310, 334–5), gives evidence of the ancient Akkadian belief that disease and sickness were caused by specific malevolent spirits which possessed the person. The demons had been eaten with the food, drunk with the water, or inbreathed from the air; and until the evil power had been expelled the victim had no chance of recovery. Exorcism was effected by the sorcerer-priest, the intermediary between mankind and the spiritual world, using magic spells consisting of the names of deities, the name signifying the personality of the god, who was compelled by this use of the name to attend to the exorcist.
Among the Semites any mysterious natural object or occurrence appealing strongly to the imagination or exciting sentiments of awe and reverence was readily taken as a manifestation either of Divine or of demonic life (W. R. Smith, RS [Note: S Religion of the Semites.] 119 ff.). The demons, if offended, avenged themselves by sending various forms of disease. Indications are found in the Gospels that such ideas were not extinct in the time of Christ. The old Semitic strain of conception was modified and quickened by contact with Babylonian, Persian, and Grecian peoples, and prevailed with considerable force in the later Judaism. The NT reflects the ideas of a time when the older conceptions were breaking up, but had not yet disappeared.
Our Lord gives no sanction to any such thought of disease, and when the disciples betrayed their mode of thought (Joh 9:2) He took occasion to combat the ancient superstition. Although He did frequently mark sin as the cause of much physical weakness and disease (see art. Impotence), yet He denies that all sickness was penal in character. Other ends were in the Divine purview besides the punishment of personal sin (Joh 9:3). In St. Luke’s Gospel high fever seems to be attributed by implication to an evil agency, and Jesus is said to have rebuked (
ii. References in the Gospels to sickness and disease.
The terms employed by the Evangelists to denote bodily ailments are—
(1)
(a) softness or effeminacy, as well as sickness; (b) periodic and chronic sickness and consequent languor of body. The word is used in Mat 4:23-24; Mat 9:35; Mat 10:1, where it is associated with
Of the presence of specific diseases much fuller indications are more or less distinctly given in the OT than in the NT. Instances of these may he understood as included in the miscellaneous cases of sickness and disease which our Lord repeatedly dealt with. Among them are various forms of skin disease, which were and are very common in the East; also of fever and allied disorders, extending to plague and pestilence; diseases of the digestive organs; infantile and senile diseases; affections of the brain or other parts of the nervous system; and disordered conditions of the psychical side of human nature. All of these are referred to in the OT with some amount of definiteness as to symptoms.
The diseases mentioned in the Gospels, and dealt with in direct and Divine fashion by Jesus (see art. Cures), include cases of physical defect; fevers and kindred diseases; skin diseases, notably that of leprosy; a solitary case of dropsy; ailments and infirmities that were nervous in character; and others which were a combination of nervous and psychical disorder. These various afflictions are not always to be certainly identified with particular forms of disease with which modern medical science is familiar. The description of the cases is, for the most part, far removed from being scientific, but yet enables us to broadly distinguish them from one another and to classify them with fair exactitude.
1. Diseases resulting in physical defect, or incapacity
(2) Defect in the organs of sense.—Among defects notably common in the East is that of blindness (see art. Sight, B). Deafness is usually accompanied by dumbness, being indeed often the main cause of it—the term deaf-mute thus accurately describing the limitation. See Deaf and Dumb.
(3) Defects in the organs both of sense and speech.—In Mat 12:22 blindness and dumbness are combined, together with mental disturbance. In this case the restoration is not spoken of as a casting out of the demon, but as a healing (
4. A solitary case of dropsy is recorded in Luk 14:2, described as
Under this head are included—
(1) Paralysis or Palsy (see art. Paralysis).
(2) Epilepsy. The cases in the NT of this distressing nervous malady are complicated with forms of mental disturbance (see art. Lunatic). But it may be supposed that among those who were regarded as possessed and whose restoration was included under the general exorcisms, some were cases of simple epilepsy (wh. see).
(3) Probably the two cases of general impotence must be included here—mentioned in Joh 5:2; Joh 5:9 and Luk 13:11-17 (see art. Impotence).
(4) In all likelihood also the man with the withered hand was one nervously afflicted. The case is recorded in Mat 12:9-13, Mar 3:1-5, Luk 6:6-11. The incapacity and wasting might be due to (a) infantile paralysis, the disease arresting the development and growth of tissue, leaving the limb shrunk and withered; or (b) it may have been congenital; or (c) it might be due to some direct injury to the main nerve of the limb, preventing its proper nutrition.
Among the halt and withered of Joh 5:3 probably there were cases of chronic rheumatism, joint diseases, and other wasting ailments, in many instances complicated with nervous exhaustion and weakness, if not with positive disease.
6. Nervous and psychical diseases.—Cases of lunacy, of epilepsy combined with insanity and perhaps those allied with idiocy, and others generally described as instances of demonic possession are given in the Gospels, and are to be recognized as having a twofold causation, on the one side physical, on the other psychical; and the problem as to which of these is primary in any particular case is not to be lightly determined. In this connexion arises the outstanding question as to the possibility of a genuine spiritual possession (see art. Lunatic), a matter which may well remain with us for some time yet as a challenge both to medical and to theological investigation. The science of anthropology may throw much light upon it, and possibly in the course of further inquiry some of the conclusions of that science may be found in need of serious modification.
Literature.—For facts relating to the nature and spread of disease in Oriental lands, and especially in Syria, consult Hirsch, Handbook of Historical Pathology (Sydenbam Soc. Tr.); Macgowan in Jewish Intelligence and Journal of Missionary Labours, 1846; Thomson, Land and Book, pp. 140–149, 356, and, for leprosy, ch. 43; also consult generally ‘Krankheiten’ in Herzog’s PRE [Note: RE Real-Encyklopädie fur protest. Theologic und Kirche.] 3 [Note: designates the particular edition of the work referred] ; Jahn, Archœologia Biblica, pt. i. ch. xii.; J. Risdon Bennett, Diseases of Bible; Hobart, Medical Language of St. Luke; Mason Good, Study of Medicine; art. by Macalister on ‘Medicine’ in Hasting’s Dictionary of the Bible . For Talmudic conception of disease and medical treatment in vogue, see Wunderhar, Biblisch-Talmudische Medicin.
T. H. Wright.
DISEASE.—See Medicine.
Exo 15:26 (c) The word may be used to symbolize the wicked habits and ways that this sinful world fastens upon those who belong to it but from which the Christians are delivered.
Psa 103:3 (c) Here it is indicated that every wrong, harmful and hurtful thing in the Christian’s life will come under the beneficent and blessed healing power of the Lord JESUS, if he wills it so.
Sickness and disease are among the results of sin that entered the human race when Adam sinned (Gen 3:16-19). Jesus’ healing of disease was one evidence that the kingdom of God had come and that Jesus had power over all the evil effects of sin (Mat 4:23; Mat 8:17; Mat 9:35; Mat 12:28). The age to come will see the complete removal of all sickness and disease (Rev 21:4; Rev 22:2).
At times God may use sickness to punish people for their sins (Num 12:1-10; 2Ki 5:25-27; Psa 38:3-6; Joh 5:13-14; Act 12:23). Other times he may use sickness to make them more reliant on his power and grace (2Co 12:7-10). In most cases, however, it is not possible to say why people suffer from sickness, disability or disease (Joh 9:1-3). The book of Job shows that no one should judge another with the accusation that the sufferer’s experience is because of personal sin (Job 42:7; see JOB; SUFFERING).
Among the diseases and disabilities that the Bible mentions are leprosy (2Ki 7:3; 2Ki 7:8; Luk 17:12; see LEPROSY), epilepsy (Mat 4:24), dysentery (Act 28:8), nervous disorders (1Sa 16:14-23; Dan 4:33), deafness (Lev 19:14; Mar 7:32), dumbness (Mar 7:37; Mar 9:25), blindness (2Sa 5:8; Mar 10:46; Joh 9:1), paralysis (Joh 5:4; Act 9:33), bone deformities (Luk 5:18; Luk 6:6; Luk 13:11), boils (1Sa 5:6; Isa 38:21), dropsy (Luk 14:2) and various fevers (Mar 1:30; Joh 4:52; Act 28:8). (Concerning the connection between demon possession and certain diseases see UNCLEAN SPIRITS.)
The Israelite laws governing cleansing, foods and diseases provided a standard of hygiene that helped protect people from many harmful diseases (see UNCLEANNESS). Nevertheless, some sickness was inevitable. At a time when the knowledge and facilities of modern medicine were not available, physicians and common people alike used whatever skills they had (Gen 50:2; Jer 8:22; Mar 5:26) and whatever treatments were available to them (2Ki 20:7; Jer 46:11; Luk 10:34; 1Ti 5:23). Many of the non-Israelite physicians were actually sorcerers (2Ch 16:12; see MAGIC).
In the bible, disease may refer to sickness, infirmity, illness, plague, and pestilence. However, plague and pestilence usually refer to situations with many victims, like epidemics. Plague and pestilence usually refer to diseases that affect many people at the same time, such as during an epidemic (a widespread outbreak). Pestilence literally means “destruction” and often describes an epidemic that causes many deaths.
Affliction and torment can sometimes include disease, but these words are broader in meaning. They may describe suffering or distress in general, not only physical illness.
During the time the Bible was written, people did not have detailed knowledge of human anatomy or of how the body’s organs worked. They did not understand disease in medical or scientific ways as people do today.
People usually thought of disease as something abnormal that weakened a person. Disease limited a person’s strength and ability to live an active life. The Hebrew word translated “sickness” is related to a verb that means “to be weak.”
This idea appears in the story of the sick man by the pool of Bethesda. He is described as an “invalid” (that is, weak and unable to move on his own) and could not get around by himself (John 5:7).
Sources of Disease
According to the Bible, disease comes from four sources:
God,
Satan,
sins of ancestors, abd
breaking physical, mental, emotional, or moral laws of nature.
God
Early people believed events and phenomena were caused by the supernatural, either by various gods or evil spirits. The Hebrews were different because they were strong monotheists. They believed one true God, who had revealed himself to them (Isaiah 45:21), was responsible for everything, including disease and evil (verse 7). This same God could also provide material blessings, health, and heal all diseases (Psalms 103:3). To the Hebrews, God could give health or sickness, and in either case, he had a purpose or reason.
One reason for disease was punishment for wrongdoing (2 Samuel 24:1, 12–16; 1 Corinthians 10:8). In the early Hebrew belief system, the response to disease was first to pray to God for forgiveness, even when the cause of disease and death was clear. For example, if venomous snakes were biting people, the first reaction was to seek God's favor, not to kill the snakes (Numbers 21:4–9). Leprosy, meaning "a smiting," was a severe disease sent by God to punish sinners (Numbers 12; 2 Kings 5:27).
God sent disease to show his power or to protect his people. The ten plagues in Egypt show his power. The destruction of Sennacherib's army shows his protection (2 Kings 19:34–36).
Satan
Satan and other evil spirits could also be responsible for disease. In the Bible, God allows Satan to bring disease. However, God limits Satan's power, as shown in the story of Job (Job 1:12). The New Testament also makes it clear that, even though Satan can influence people in certain ways, his time is limited. His complete defeat and destruction are certain.
Sins of Ancestors
Diseases in the Bible were also assumed at times to result from the sins of one's ancestors (Exodus 20:5; Leviticus 26:29; 1 Kings 17:18; Job 21:19; Lamentations 5:7). A notable example is the death of David's son due to his sin with Bathsheba (2 Samuel 12:15). This idea of disease origins continued into New Testament times and was known to the disciples of Jesus (John 9:2).
Breaking Natural Laws
This idea distinguishes the Hebrews from other peoples of their time. They believed that breaking physical, mental, emotional, or moral laws could lead to disease. This belief introduced the idea of personal responsibility for following these laws to avoid illness. A person is responsible for their own health and the community's health, rather than being a passive victim of supernatural forces.
Moses created detailed rules for personal and community health. The Mosaic law includes guidelines for many elements of life, including:
diet,
personal hygiene,
observing the Sabbath,
sanitary regulations in the camp,
cleanliness, and
sexual relations.
By following these natural laws from God, the Hebrews could expect to avoid disease (Exodus 15:26) and live long lives (Proverbs 3:1–2). From a public health perspective, these health laws of Moses are still sensible today. Many of the health laws are now demonstrably more logical than those in many other ancient cultures.
Understanding that disease can result from breaking natural laws led to a shift from priests to physicians for cures. When people thought diseases were supernatural, they did not try to learn about them to find cures. The Hebrews knew about physicians in Egypt (Genesis 50:2), where they likely worked as embalmers. Physicians practiced in Israel throughout its history, but their ability to help improved slowly (2 Chronicles 16:12; Jeremiah 8:22; Mark 5:26; Colossians 4:14). While the Scriptures support using physicians for the sick (Matthew 9:12) and medicinal drugs (Proverbs 31:6; 1 Timothy 5:23), they highlight the Christian community and its elders' role in caring for the sick (James 5:14).
Jesus Christ and Disease
Jesus treated people with diseases differently from how they were treated in the Old Testament. He did not judge them. He saw them as valuable individuals, not outcasts. He showed true compassion by touching, comforting, healing, and speaking to them naturally.
Jesus saw disease as something that stopped people from being their true selves. When he met a woman with a severe back problem for 18 years, he healed her, saying she had been "bound by Satan" (Luke 13:16). His healing of incurable diseases showed he was the Messiah (Luke 7:19–23). His work aimed to help people live more fully (John 10:10). He did not fully agree with the idea that disease was a punishment (9:3). When a leper suggested it might not be God's will for him to be well, Jesus healed him immediately (Mark 1:40; Luke 5:12–13).
Jesus was always concerned with the person’s total health or wholeness, rather than merely the symptoms of disease. He often addressed spiritual issues first, even when someone came to him with a physical problem. His talk with the Samaritan woman at the well focused on her inner conflicts (John 4:5–30). And the Sermon on the Mount, which basically deals with right attitudes and motives for human behavior, would greatly reduce personal and social suffering if it were followed. To Jesus, health is more than the absence of physical or mental disease. Health means that people are whole and able to live as God intended them to live.
See also Medicine and Medical Practice; Diseases; Plague.
Aquifer Open Bible Dictionary © 2026 Mission Mutual, an adaptation of the Tyndale Open Bible Dictionary © 2023 Tyndale House Publishers. Licensed under CC BY-SA 4.0.
An illness or other condition which prevents people or animals from achieving their full potential or adversely affects their abilities.
General and specific examples of disease
General references
MAT 8:17; MRK 3:10 See also EXO 15:26; DEU 7:15; 2CH 16:12; JHN 5:3; ACT 28:9
Blindness
Boils and sores
EXO 9:9; ; JOB 2:7; ; ISA 38:21; ; LUK 16:20
Depression
Dropsy
See also LUK 14:2
Dysentery
Epilepsy
MAT 17:15 See also MAT 4:24; MRK 9:17–9:18
Fever
JOB 30:30 See also MAT 8:14 parallels MRK 1:30, LUK 4:38; ACT 28:8
Haemorrhaging
MAT 9:20 parallels MRK 5:25, LUK 8:43
Inflammation
Insanity
Leprosy
NUM 12:10; ; 2CH 26:21; ; MAT 11:5; ; LUK 17:11–17:19
Paralysis
MAT 4:24, MAT 8:6, MAT 9:2 parallels MRK 2:3, LUK 5:18; ; LUK 13:11; ; ACT 3:2, ACT 8:7, ACT 9:33
Sunstroke
2KI 4:18–4:19; ; PSA 121:5–121:6; ; ISA 49:10; ; JON 4:8
Tumours
Voluntary starvation
1SA 1:7, 1SA 28:20; ; PSA 102:4, PSA 107:18
Wasting
Even the righteous suffer disease
JOB 2:3, JOB 2:7 See also PSA 38:2–38:3, PSA 41:7–41:8
Examples of the righteous suffering
2KI 20:1 parallel 2CH 32:24; ; DAN 8:27; ; LUK 7:2; ; JHN 11:1; ; ACT 9:36–9:37; ; GAL 4:13; ; PHP 2:25–2:27; ; 1TI 5:23; ; 2TI 4:20
Causes of disease
Original sin
Accident
See also 2KI 4:39–4:40
Judgment
PSA 107:17–107:18 See also EXO 9:8–9:10; LEV 26:14–26:16; NUM 16:41–16:49; 2KI 5:27; JER 14:12; 1CO 11:29–11:30
Testing
Response to sickness and disease
The compassion of God
MRK 1:32–1:34 See also PSA 41:3; MAT 8:17
Compassion
EZK 34:4; ; MAT 25:36; ; LUK 9:2, LUK 10:30–10:37
Humble submission
JOB 13:15 See also 2CO 12:8–12:10
Prayer
JAS 5:14 See also GEN 20:17; 2CO 12:8
Spiritual disease
ISA 1:5–1:6 See also JER 8:22, JER 30:12; MIC 1:9; MAT 9:12–9:13 parallel LUK 5:31–5:32
Salvation and healing from disease
Salvation achieved through the cross of Jesus Christ
Salvation made perfect in heaven
REV 22:1–22:3 See also EZK 47:12; REV 7:17, REV 21:1–21:4
Dictionary of Bible Themes © 1999 Martin H. Manser. Licensed under CC BY-SA 4.0.
